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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using tacrolimus and call your doctor at once if you have a serious side effect such as:

  • severe stinging, burning, itching, or soreness where the medicine is applied;

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  • redness or crusting around your hair follicles; or

  • signs of a skin infection (redness, swelling, itching, oozing).

Less serious side effects may include:

  • mild burning, stinging, or itching;

  • skin redness;

  • acne;

  • cold or flu symptoms such as stuffy nose, sneezing, sore throat;

  • headache; or

  • feeling more sensitive to hot or cold temperatures.

This is not a complete list of side effects and others may occur.

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